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What is Delirium?

Delirium, also known as acute confusional state, is a disturbance in mental abilities that involves inattention, awareness and cognition. It tends to have a rapid onset and fluctuating course. Delirium is fairly common, especially among hospitalized elderly patients, occurring in up to 30% of cases.
There are three main types of delirium:

1 . Hyperactive delirium involves agitation, restlessness and sometimes hallucinations.
2 . Hypoactive delirium involves sleepiness, sluggishness and reduced responsiveness.
3 . Mixed delirium fluctuates between hyperactive and hypoactive states.

Cause

Delirium is caused by an underlying medical condition or from medication effects, substance intoxication or withdrawal. Some common causes include infections, electrolyte imbalances, organ failure, surgery and medications with anticholinergic properties. Delirium often results from multiple factors occurring together that disrupt normal brain functioning.

Symptoms

The core symptom is inattention – reduced ability to focus, sustain or shift attention. Other cognitive deficits include memory impairment, disorientation, language disturbance, and perceptual issues like hallucinations and delusions. There may also be mood changes, anxiety, agitation, activity changes and sleep-wake cycle disruption.

Diagnosis

Delirium needs prompt assessment and management to identify underlying causes and prevent complications. Screening tools like the Confusion Assessment Method allow clinicians to assess the severity and features. Lab tests, brain imaging and medication reviews help diagnose causes.

Treatments

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The main treatment is addressing the underlying illness or toxicity triggering delirium through appropriate medical care. Providing a calm, well-lit environment, reorienting the person and having familiar faces around can help reduce agitation and disorientation. Antipsychotics are sparingly used for severe agitation or psychosis.

The biggest priority is preventing the complications of delirium. Immobility can lead to bedsores, blood clots and muscle wasting. Difficulty eating and drinking may cause malnutrition and dehydration.Inattention and disorientation also increase the risks of falls and injury. Careful nursing care and emotional support are vital.

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